Landing Proteins on Graphene Trampoline Preserves Their Gas-Phase Folding on the Surface.

ABSTRACT: Molecule-surface collisions are known to initiate dynamics that lead to products inaccessible by thermal chemistry. These collision dynamics, however, have mostly been examined on bulk surfaces, leaving vast opportunities unexplored for molecular collisions on nanostructures, especially on those that exhibit mechanical properties radically different from those of their bulk counterparts. Probing energy-dependent dynamics on nanostructures, particularly for large molecules, has been challenging due to their fast time scales and high structural complexity. Here, by examining the dynamics of a protein impinging on a freestanding, single-atom-thick membrane, we discover molecule-on-trampoline dynamics that disperse the collision impact away from the incident protein within a few picosec

SUBMITTER: Anggara K 

PROVIDER: S-EPMC9951278 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature