A multicenter evaluation of antibacterial use in hospitalized patients through the SARS-Cov-2 pandemic waves.

ABSTRACT:

Background

Excessive use of antibiotics has been reported during the SARS-CoV-2 pandemic. We evaluated trends in antibiotic use and culture positive Gram-negative (GN)/Gram-positive (GP) pathogens in US hospitalized patients before and during the SARS-CoV-2 pandemic.

Methods

This multicenter, retrospective study included patients from 271 US facilities with > 1-day inpatient admission with discharge or death between July 1, 2019, and October 30, 2021, in the BD Insights Research Database. We evaluated microbiological testing data, antibacterial use, defined as antibacterial use ≥ 24 h in admitted patients, and duration of antibacterial therapy.

Results

Of 5,518,744 patients included in the analysis, 3,729,295 (67.6%) patients were hospitalized during the pandemic with

SUBMITTER: Puzniak LA 

PROVIDER: S-EPMC9951830 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature