Genomic Evidence for Direct Transmission of mecC-MRSA between a Horse and Its Veterinarian.

ABSTRACT: Methicillin-resistant Staphylococcus aureus bearing the mecC gene (mecC-MRSA) has been reported from animals and humans in recent years. This study describes the first mecC-MRSA isolates of human and equine origin in Hungary (two isolates from horses and one from a veterinarian, who treated one of the infected horses, but was asymptomatic). MRSA isolates were identified by cultivation and PCR detection of the species-specific spa gene and mecA/mecC methicillin resistance genes. The isolates were characterized by antibiotic susceptibility testing, MLST, spa, SCCmec typing, PFGE and whole genome sequencing (WGS). All three isolates belonged to the ST130-t843-SCCmec XI genotype, and carried the mecC and blaZ g

SUBMITTER: Albert E 

PROVIDER: S-EPMC9952710 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature