Ontology highlight
ABSTRACT:
SUBMITTER: Marciano G
PROVIDER: S-EPMC9953417 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Marcianò Gianmarco G Vocca Cristina C Rania Vincenzo V Citraro Rita R De Sarro Giovambattista G Gallelli Luca L
Biomolecules 20230131 2
Matrix metalloproteinases (MMPs) are a large family of zinc-dependent proteolytic enzymes associated with extracellular matrix protein turnover and tissue degradation. They participate to many different physiological reactions but are also hyperactivated in several diseases. Various literature studies have documented that MMPs play a role in the modulation of neuropathic and nociceptive pain. The heterogeneity of clinical and pre-clinical data is an important issue in this experimental context. ...[more]