Porphyrin-Based Covalent Organic Frameworks with Donor-Acceptor Structure for Enhanced Peroxidase-like Activity as a Colorimetric Biosensing Platform.

ABSTRACT: Hydrogen peroxide (H₂O₂) and glucose play a key role in many cellular signaling pathways. The efficient and accurate in situ detection of H₂O₂ released from living cells has attracted extensive research interests. Herein, a new porphyrin-based porous covalent organic framework (TAP-COF) was fabricated via one-step condensation of 1,6,7,12-tetrachloroperylene tetracarboxylic acid dianhydride and 5,10,15,20-tetrakis (4-aminophenyl)porphyrin iron(III). The obtained TAP-COF has high surface areas, abundant surface catalytic active sites, and highly effective electron transport due to its precisely controllable donor-acceptor arrangement and 3D porous structure. Then, the new TAP-COF exhibited excellent peroxidase-like catalytic activity, which could

SUBMITTER: Wang Q 

PROVIDER: S-EPMC9953433 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature