Pre-Stimulus Power but Not Phase Predicts Prefrontal Cortical Excitability in TMS-EEG.

ABSTRACT: The cortical response to transcranial magnetic stimulation (TMS) has notable inter-trial variability. One source of this variability can be the influence of the phase and power of pre-stimulus neuronal oscillations on single-trial TMS responses. Here, we investigate the effect of brain oscillatory activity on TMS response in 49 distinct healthy participants (64 datasets) who had received single-pulse TMS over the left dorsolateral prefrontal cortex. Across all frequency bands of theta (4-7 Hz), alpha (8-13 Hz), and beta (14-30 Hz), there was no significant effect of pre-TMS phase on single-trial cortical evoked activity. After high-powered oscillations, whether followed by a TMS pulse or not, the subsequent activity was larger than after low-powered oscillations. We further defined a measu

SUBMITTER: Poorganji M 

PROVIDER: S-EPMC9953459 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature