Transcriptional Analysis of the Endostyle Reveals Pharyngeal Organ Functions in Ascidian.

ABSTRACT: The endostyle is a pharyngeal organ with an opening groove and cilia in invertebrate chordates (amphioxus and ascidian) and cyclostomate (lamprey), serving as a filter-feeding tract and thyroid-secreting location. Emerging evidence implies its complex cellular composition and potentially versatile functions. Multiple cell types in the endostyle have been thought to be progenitors of complex organs in advanced vertebrates. To describe the expression profile and the potential functions, bulk RNA sequencing on the endostyle in ascidian Styela clava was conducted and distinct markers were selected by multileveled comparative analysis. Transcriptional data assay and qRT-PCR-verified results showed the regional expression patterns of Hox genes in the longitudinal axis. Organ-specific mark

SUBMITTER: Jiang A 

PROVIDER: S-EPMC9953650 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature