The Prognostic Value of DCE-MRI Findings before Salvage Radiotherapy after Radical Prostatectomy.

ABSTRACT:

Background

To investigate the predictive role of dynamic contrast-enhanced-magnetic resonance imaging (DCE-MRI) findings before salvage radiotherapy after radical prostatectomy (RP).

Methods

This retrospective study selected patients with biochemical failure (BF) after RP restaged with DCE-MRI. Patients underwent sRT in 30 fractions delivering 66-69 Gy and 73.5 Gy to the prostatic fossa and to the local failure as per DCE-MRI, respectively. Pelvic nodes were treated to 54 Gy in selected patients. The endpoint was BF after sRT.

Results

In total, 236 patients were analyzed and 146 (61.9%) had presumed local failure at DCE-MRI: 54.8%, 23.8% and 21.4% were found at the vesico-urethral anastomosis (VUA), the bladder neck and the retro-vesical space, respectively. The prese

SUBMITTER: Farneti A 

PROVIDER: S-EPMC9954112 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature