Potential miRNA Use as a Biomarker: From Breast Cancer Diagnosis to Metastasis.

ABSTRACT: Breast cancer is the most common cancer in women. Despite advances in diagnosis and prognosis, distal metastases occur in these patients in up to 15% of cases within 3 years of diagnosis. The main organs in which BC metastasises are the bones, lungs, liver, and brain. Unfortunately, 90% of metastatic patients will die, making this an incurable disease. Researchers are therefore seeking biomarkers for diagnosis and metastasis in different organs. Optimally, such biomarkers should be easy to detect using, preferably, non-invasive methods, such as using miRNA molecules, which are small molecules of about 22 nt that have as their main function the post-transcriptional regulation of genes. Furthermore, due to their uncomplicated detection and reproducibility in the laboratory, they are a tool o

SUBMITTER: Jordan-Alejandre E 

PROVIDER: S-EPMC9954167 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature