PEDOT-Polyamine-Based Organic Electrochemical Transistors for Monitoring Protein Binding.

ABSTRACT: The fabrication of efficient organic electrochemical transistors (OECTs)-based biosensors requires the design of biocompatible interfaces for the immobilization of biorecognition elements, as well as the development of robust channel materials to enable the transduction of the biochemical event into a reliable electrical signal. In this work, PEDOT-polyamine blends are shown as versatile organic films that can act as both highly conducting channels of the transistors and non-denaturing platforms for the construction of the biomolecular architectures that operate as sensing surfaces. To achieve this goal, we synthesized and characterized films of PEDOT and polyallylamine hydrochloride (PAH) and employed them as conducting channels in the construction of OECTs. Next, we studied the response

SUBMITTER: Montero-Jimenez M 

PROVIDER: S-EPMC9954629 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature