Multi-Parameter Detection of Urine Based on Electropolymerized PANI: PSS/AuNPs/SPCE.

ABSTRACT: Urine analysis is widely used in clinical practice to indicate human heathy status and is important for diagnosing chronic kidney disease (CKD). Ammonium ions (NH₄⁺), urea, and creatinine metabolites are main clinical indicators in urine analysis of CKD patients. In this paper, NH₄⁺ selective electrodes were prepared using electropolymerized polyaniline-polystyrene sulfonate (PANI: PSS), and urea- and creatinine-sensing electrodes were prepared by modifying urease and creatinine deiminase, respectively. First, PANI: PSS was modified on the surface of an AuNPs-modified screen-printed electrode, as a NH₄⁺-sensitive film. The experimental results showed that the detection range of the NH₄⁺ selective electr

SUBMITTER: Wang D 

PROVIDER: S-EPMC9954737 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature