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Isolation, characterization, therapeutic potency, and genomic analysis of a novel bacteriophage vB_KshKPC-M against carbapenemase-producing Klebsiella pneumoniae strains (CRKP) isolated from Ventilator-associated pneumoniae (VAP) infection of COVID-19 patients.

ABSTRACT:

SUBMITTER: Mohammadi M

PROVIDER: S-EPMC9955523 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Isolation, characterization, therapeutic potency, and genomic analysis of a novel bacteriophage vB_KshKPC-M against carbapenemase-producing Klebsiella pneumoniae strains (CRKP) isolated from Ventilator-associated pneumoniae (VAP) infection of COVID-19 patients.

Mohammadi Mehrdad M Saffari Mahmood M Siadat Seyed Davar SD Hejazi Seyed Hossein SH Shayestehpour Mohammad M Motallebi Mitra M Eidi Milad M

Annals of clinical microbiology and antimicrobials 20230224 1

<h4>Background</h4>Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a significant clinical problem, given the lack of therapeutic options. The CRKP strains have emerged as an essential worldwide healthcare issue during the last 10 years. Global expansion of the CRKP has made it a significant public health hazard. We must consider to novel therapeutic techniques. Bacteriophages are potent restorative cases against infections with multiple drug-resistant bacteria. The Phages offer promising pr ...[more]

PMID: 36829156

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