Hemorrhagic Shock: Blood Marker Sequencing and Pulmonary Gas Exchange.

ABSTRACT:

Background

The early identification of internal hemorrhage in critically ill patients may be difficult. Besides circulatory parameters, hemoglobin and lactate concentration, metabolic acidosis and hyperglycemia serve as laboratory markers for bleeding. In this experiment, we examined pulmonary gas exchange in a porcine model of hemorrhagic shock. Moreover, we sought to investigate if a chronological order of appearance regarding hemoglobin, lactatemia, standard base excess/deficit (SBED) and hyperglycemia exists in early severe hemorrhage.

Methods

In this prospective, laboratory study, twelve anesthetized pigs were randomly allocated to exsanguination or a control group. Animals in the exsanguination group (n = 6) endured a 65% blood loss over 20 min. No intravenous f

SUBMITTER: Treml B 

PROVIDER: S-EPMC9955920 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature