Transcriptomic Analysis of Long Non-Coding RNA during Candida albicans Infection.

ABSTRACT: Candida albicans is one of the most commonly found species in fungal infections. Due to its clinical importance, molecular aspects of the host immune defense against the fungus are of interest to biomedical sciences. Long non-coding RNAs (lncRNAs) have been investigated in different pathologies and gained widespread attention regarding their role as gene regulators. However, the biological processes in which most lncRNAs perform their function are still unclear. This study investigates the association between lncRNAs with host response to C. albicans using a public RNA-Seq dataset from lung samples of female C57BL/6J wild-type Mus musculus with induced C. albicans infection. The animals were exposed to the fungus for 24 h before sample collection. We selected ln

SUBMITTER: Goncalves GF 

PROVIDER: S-EPMC9956080 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature