Factors Associated with Chronic Kidney Disease of Unknown Etiology (CKDu): A Systematic Review.

ABSTRACT: (1) Background: Despite ample research, the factors, specific causes, and pathways associated with chronic kidney disease of unknown etiology (CKDu) remain elusive. Therefore, we performed a systematic review to explore the potential etiologies for the development of CKDu globally. (2) Methods: A systematic literature review was conducted using databases CINAHL, Cochrane Library, Embase, Google Scholar, MEDLINE, and PsycINFO on the specific causes and pathophysiology related to CKDu from inception until April 2021. Study selection, data extraction of included articles, and quality appraisal were assessed. The narrative approach was used to summarize and comprehend the findings. (3) Results: Our study included 25 studies, considering 38,351 participants. Twelve studies were case-control, te

SUBMITTER: Nayak S 

PROVIDER: S-EPMC9956943 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature