Dyslipidemia and impaired liver function biomarkers in patients with hepatitis B liver cirrhosis.

ABSTRACT:

Objective

This study was conducted to determine changes in lipid metabolism and liver enzyme status among HBV-positive patients with liver cirrhosis.

Methods

A total of 300 HBV-positive patients with liver cirrhosis and 200 healthy controls were included in this case-control study. The patients were recruited from several tertiary care hospitals in Lahore from March to October 2021. Their blood samples were collected and analyzed for HBsAg, HBeAg, liver function biomarkers, and serum lipids. Liver cirrhosis was confirmed by ultrasonography and liver biopsy. The data were analyzed with chi-square test, Student's t-test, logistic regression, and ROC curve analysis.

Results

Serum liver function biomarkers were significantly higher, and serum lipid levels were substantial

SUBMITTER: Shoaib N 

PROVIDER: S-EPMC9957755 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature