Restricted mean survival time versus conventional effect summary for treatment decision-making: A mixed-methods study.

ABSTRACT:

Background

Treatment effect is typically summarized in terms of relative risk reduction or number needed to treat ("conventional effect summary"). Restricted mean survival time (RMST) summarizes treatment effect in terms of a gain or loss in event-free days. Older adults' preference between the two effect summary measures has not been studied.

Methods

We conducted a mixed methods study using a quantitative survey and qualitative semi-structured interviews. For the survey, we enrolled 102 residents with hypertension at five senior housing facilities (mean age 81.3 years, 82 female, 95 white race). We randomly assigned respondents to either RMST-based (n = 49) or conventional decision aid (n = 53) about the benefits and harms of intensive versus standard blood pressure-lowerin

SUBMITTER: Shi SM 

PROVIDER: S-EPMC9957827 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature