Role of factor VIII, IX, and XI in venous thrombosis recurrence risk in adults and children: A systematic review.

ABSTRACT:

Background

Predicting recurrent venous thromboembolic events (VTEs) is challenging in clinical practice for both adults and children, but it is relevant for clinical management. Identifying laboratory risk factors for VTE recurrence may aid in clinical decision-making.

Objective

The goal of this systematic review is to investigate the predictive role of FVIII, IX, or XI in recurrent VTE in adult and pediatric patients with a first VTE.

Methods

A systematic review of the published literature was conducted in databases MEDLINE In-Process, Other Nonindexed Citations, MEDLINE Epub Ahead of Print, EMBASE Classic + EMBASE (OvidSP), and Cochrane (Wiley). We included observational and interventional studies that comprised adults or children with a first VTE, FVIII, FIX, and/o

SUBMITTER: Bosch A 

PROVIDER: S-EPMC9958483 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature