Muscle distribution in relation to all-cause and cause-specific mortality in young and middle-aged adults.

ABSTRACT:

Background

The relationship between muscle and prognosis, especially that between muscle distribution across different body parts, and the related prognosis is not well established.

Objective

To investigate the relationship between muscle distribution and all-cause and cause-specific mortality and their potential modifiers.

Design

Longitudinal cohort study. C-index, IDI, and NRI were used to determine the best indicator of prognosis. COX regression analysis was performed to explore the relationship between variables and outcomes. Interaction and subgroup analyses were applied to identify the potential modifiers.

Participants

A total of 5052 participants (weighted: 124,841,420) extracted from the NHANES 2003-2006 of median age 45 years and constituting 50.3% men

SUBMITTER: Liu CA 

PROVIDER: S-EPMC9960213 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature