Effects of Fe²⁺ addition to sugarcane molasses on poly-γ-glutamic acid production in Bacillus licheniformis CGMCC NO. 23967.

ABSTRACT:

Background

Poly-γ-glutamic acid (γ-PGA) is biodegradable, water-soluble, environment-friendly, and edible. Consequently, it has a variety of industrial applications. It is crucial to control production cost and increase output for industrial production γ-PGA.

Results

Here γ-PGA production from sugarcane molasses by Bacillus licheniformis CGMCC NO. 23967 was studied in shake-flasks and bioreactors, the results indicate that the yield of γ-PGA could reach 40.668 g/L in a 5L stirred tank fermenter. Further study found that γ-PGA production reached 70.436 g/L, γ-PGA production and cell growth increased by 73.20% and 55.44%, respectively, after FeSO₄·7H₂O was added. Therefore, we investigated the metabolomic and transcriptomic changes following FeSO₄

SUBMITTER: Guo L 

PROVIDER: S-EPMC9960700 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature