Electrospun Scaffolds Based on Poly(butyl cyanoacrylate) for Tendon Tissue Engineering.

ABSTRACT: Tendon disorders are common medical conditions that could lead to significant disability, pain, healthcare costs, and a loss of productivity. Traditional approaches require long periods of treatment, and they largely fail due to the tissues weakening and the postoperative alterations of the normal joint mechanics. To overcome these limitations, innovative strategies for the treatment of these injuries need to be explored. The aim of the present work was the design of nano-fibrous scaffolds based on poly(butyl cyanoacrylate) (PBCA), a well-known biodegradable and biocompatible synthetic polymer, doped with copper oxide nanoparticles and caseinphosphopeptides (CPP), able to mimic the hierarchical structure of the tendon and to improve the tissue healing potential. These were developed as imp

SUBMITTER: Bianchi E 

PROVIDER: S-EPMC9960733 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature