Do Patients with Bronchiectasis Have an Increased Risk of Developing Lung Cancer? A Systematic Review.

ABSTRACT:

Background

Initial evidence supports the hypothesis that patients with non-cystic fibrosis bronchiectasis (NCFB) have a higher risk of lung cancer. We systematically reviewed the available literature to define the characteristics of lung malignancies in patients with bronchiectasis and the characteristics of patients who develop bronchiectasis-associated lung cancer.

Method

This study was performed based on the PRISMA guidelines. The review protocol was registered in PROSPERO.

Results

The frequency rates of lung cancer in patients with NCFB ranged from 0.93% to 8.0%. The incidence rate was 3.96. Cancer more frequently occurred in the elderly and males. Three studies found an overall higher risk of developing lung cancer in the NCFB population compared to the non-bronc

SUBMITTER: Castaldo N 

PROVIDER: S-EPMC9961135 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature