Structure and Microbiological Activity of 1H-benzo[d]imidazole Derivatives.

ABSTRACT: Three new crystal structures of 1H-benzo[d]imidazole derivatives were determined. In the structures of these compounds, an identical system of hydrogen bonds, C(4), was observed. Solid-state NMR was applied for testing the quality of the obtained samples. All of these compounds were tested for in vitro antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, as well as antifungal activity, by checking their selectivity. ADME calculations indicate that the compounds can be tested as potential drugs.

SUBMITTER: Olczak A 

PROVIDER: S-EPMC9961232 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature