Histopathological Lung Findings in COVID-19 B.1.617.2 SARS-CoV-2 Delta Variant.

ABSTRACT:

Background

The Delta variant (Pango lineage B.1.617.2) is one of the most significant and aggressive variants of SARS-CoV-2. To the best of our knowledge, this is the first paper specifically studying pulmonary morphopathology in COVID-19 caused by the B.1.617.2 Delta variant.

Methods

The study included 10 deceased patients (40-83 years) with the COVID-19 Delta variant. The necrotic lung fragments were obtained either by biopsy (six cases) or autopsy (four cases). Tissue samples were subjected to virology analysis for identification of the SARS-CoV-2 variant, histopathology, and immunohistochemistry (anti-SARS coronavirus mouse anti-virus antibody).

Results

Virology analysis identified B.1.617.2 through genetic sequencing in eight cases, and in two cases, specific mut

SUBMITTER: Jeican II 

PROVIDER: S-EPMC9961426 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature