Extracellular Vesicles as New Players in Drug Delivery: A Focus on Red Blood Cells-Derived EVs.

ABSTRACT: The article is divided into several sections, focusing on extracellular vesicles' (EVs) nature, features, commonly employed methodologies and strategies for their isolation/preparation, and their characterization/visualization. This work aims to give an overview of advances in EVs' extensive nanomedical-drug delivery applications. Furthermore, considerations for EVs translation to clinical application are summarized here, before focusing the review on a special kind of extracellular vesicles, the ones derived from red blood cells (RBCEVs). Generally, employing EVs as drug carriers means managing entities with advantageous properties over synthetic vehicles or nanoparticles. Besides the fact that certain EVs also reveal intrinsic therapeutic characteristics, in regenerative medicine, EVs na

SUBMITTER: Biagiotti S 

PROVIDER: S-EPMC9961903 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature