¹H NMR Profiling of the Venom from Hylesia continua: Implications of Small Molecules for Lepidopterism.

ABSTRACT: Lepidopterism caused by caterpillar contact is considered a public health problem around the world. The local and systemic responses of this pathology include short- and long-term inflammatory events. Although the proteolytic activity of the venoms from caterpillars is strongly associated with an inflammatory response in humans and murine models, fast and acute symptoms such as a burning sensation, itching, and pain should be related to the presence of low-weight hydrophilic molecules which easily influence cell metabolism. This investigation reports on the ¹H-Nuclear Magnetic Resonance (NMR) profiling of the venom from the larva of Hylesia continua, a caterpillar linked to frequent cases of lepidopterism in the northern highlands of Puebla, Mexico. According to one-dimen

SUBMITTER: Villa-Ruano N 

PROVIDER: S-EPMC9962855 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature