An Overview of Mycoviral Curing Strategies Used in Evaluating Fungal Host Fitness.

ABSTRACT: The number of novel mycoviruses is increasing at a high pace due to advancements in sequencing technologies. As a result, an uncountable number of mycoviral sequences are available in public sequence repositories. However, only genomic information is not sufficient to understand the impact of mycoviruses on their host biology. Biological characterization is required to determine the nature of mycoviruses (cryptic, hypervirulent, or hypovirulent) and to search for mycoviruses with biocontrol and therapeutic potential. Currently, no particular selective method is used as the gold standard against these mycoviral infections. Given the importance of curing, we present an overview of procedures used in preparation of isogenic lines, along with their benefits and drawbacks. We concluded that a c

SUBMITTER: Khan HA 

PROVIDER: S-EPMC9963364 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature