Reduction of embryonic E93 expression as a hypothetical driver of the evolution of insect metamorphosis.

ABSTRACT: The early embryo of the cockroach Blattella germanica exhibits high E93 expression. In general, E93 triggers adult morphogenesis during postembryonic development. Here we show that E93 is also crucial in early embryogenesis in the cockroach, as a significant number of E93-depleted embryos are unable to develop the germ band under maternal RNAi treatment targeting E93. Moreover, transcriptomic analysis indicates that E93 depletion results in important gene expression changes in the early embryo, and many of the differentially expressed genes are involved in development. Then, using public databases, we gathered E93 expression data in embryo and preadult stages, finding that embryonic expression of E93 is high in hemimetabolan species (whose juveniles, or n

SUBMITTER: Fernandez-Nicolas A 

PROVIDER: S-EPMC9963766 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature