Inborn Errors of Immunity Causing Pediatric Susceptibility to Fungal Diseases.

ABSTRACT: Inborn errors of immunity are a heterogeneous group of genetically determined disorders that compromise the immune system, predisposing patients to infections, autoinflammatory/autoimmunity syndromes, atopy/allergies, lymphoproliferative disorders, and/or malignancies. An emerging manifestation is susceptibility to fungal disease, caused by yeasts or moulds, in a superficial or invasive fashion. In this review, we describe recent advances in the field of inborn errors of immunity associated with increased susceptibility to fungal disease.

SUBMITTER: Olbrich P 

PROVIDER: S-EPMC9964687 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature