Crosstalk of Inflammatory Cytokines within the Breast Tumor Microenvironment.

ABSTRACT: Several immune and immunocompetent cells, including dendritic cells, macrophages, adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the complex discipline of oncology. Cytotoxic innate and adaptive immune cells can block tumor proliferation, and others can prevent the immune system from rejecting malignant cells and provide a favorable environment for tumor progression. These cells communicate with the microenvironment through cytokines, a chemical messenger, in an endocrine, paracrine, or autocrine manner. These cytokines play an important role in health and disease, particularly in host immune responses to infection and inflammation. They include chemokines, interleukins (ILs), adipokines, interferons, colony-stimulating factors (CSFs), and tumor n

SUBMITTER: Habanjar O 

PROVIDER: S-EPMC9964711 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature