Retrospective Insights of the COVID-19 Epidemic in the Major Latin American City, Sao Paulo, Southeastern Brazil.

ABSTRACT: São Paulo is the financial center of Brazil, with a population of over 12 million, that receives travelers from all over the world for business and tourism. It was the first city in Brazil to report a case of COVID-19 that rapidly spread across the city despite the implementation of the restriction measures. Despite many reports, much is still unknown regarding the genomic diversity and transmission dynamics of this virus in the city of São Paulo. Thus, in this study, we provide a retrospective overview of the COVID-19 epidemic in São Paulo City, Southeastern, Brazil, by generating a total of 9995 near-complete genome sequences from all the city's different macro-regions (North, West, Central, East, South, and Southeast). Our analysis revealed that multiple independent introduction events

SUBMITTER: Assato PA 

PROVIDER: S-EPMC9965911 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature