Fast and Accurate Identification of Candida auris by High Resolution Mass Spectrometry.

ABSTRACT: The emerging pathogen Candida auris has been associated with nosocomial outbreaks on six continents. Genetic analysis indicates simultaneous and independent emergence of separate clades of the species in different geographical locations. Both invasive infection and colonization have been observed, warranting attention due to variable antifungal resistance profiles and hospital transmission. MALDI-TOF based identification methods have become routine in hospitals and research institutes. However, identification of the newly emerging lineages of C. auris yet remains a diagnostic challenge. In this study an innovative liquid chromatography (LC)-high resolution Orbitrap^TM mass spectrometry method was used for identification of C. auris from axenic microbial cultu

SUBMITTER: Jamalian A 

PROVIDER: S-EPMC9966097 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature