NaF-PET Imaging of Atherosclerosis Burden.

ABSTRACT: The method of 18F-sodium fluoride (NaF) positron emission tomography/computed tomography (PET/CT) of atherosclerosis was introduced 12 years ago. This approach is particularly interesting because it demonstrates microcalcification as an incipient sign of atherosclerosis before the development of arterial wall macrocalcification detectable by CT. However, this method has not yet found its place in the clinical routine. The more exact association between NaF uptake and future arterial calcification is not fully understood, and it remains unclear to what extent NaF-PET may replace or significantly improve clinical cardiovascular risk scoring. The first 10 years of publications in the field were characterized by heterogeneity at multiple levels, and it is not clear how the method may contribut

SUBMITTER: Hoilund-Carlsen PF 

PROVIDER: S-EPMC9966512 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature