Immunotherapy for Prostate Cancer: A Current Systematic Review and Patient Centric Perspectives.

ABSTRACT: Prostate cancer is the most commonly diagnosed cancer in men worldwide, making up 21% of all cancer cases. With 345,000 deaths per year owing to the disease, there is an urgent need to optimize prostate cancer care. This systematic review collated and synthesized findings of completed Phase III clinical trials administering immunotherapy; a current clinical trial index (2022) of all ongoing Phase I-III clinical trial records was also formulated. A total of four Phase III clinical trials with 3588 participants were included administering DCVAC, ipilimumab, personalized peptide vaccine, and the PROSTVAC vaccine. In this original research article, promising results were seen for ipilimumab intervention, with improved overall survival trends. A total of 68 ongoing trial records pooling in 7923

SUBMITTER: Rehman LU 

PROVIDER: S-EPMC9966657 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature