Postoperative Nausea and Vomiting According to Target-Controlled or Manual Remifentanil Infusion in Gynecological Patients Undergoing Pelviscopic Surgery: A Randomized Controlled Trial.

ABSTRACT:

Background

We compared the incidence of postoperative nausea and vomiting (PONV) and postoperative outcomes, according to the remifentanil infusion method, during surgery in patients with a high-risk of PONV.

Methods

Ninety patients undergoing elective gynecological pelviscopic surgery were randomly allocated to either target-controlled infusion (TCI, T) or manual (M) infusion. The primary outcome was the incidence of PONV until postoperative day (POD) 2. The secondary outcomes were perioperative heart rate (HR), blood pressure (BP), numerical rating scale pain scores up to POD2, and postoperative hospital length of stay.

Results

Forty-four patients in the T group and 45 patients in the M group were analyzed. The total dose of remifentanil infusion was significantly h

SUBMITTER: Lee S 

PROVIDER: S-EPMC9966727 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature