Effect of Digitalis on ICD or CRT-D Recipients: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Digitalis has been widely utilized for heart failure therapy and several studies have demonstrated an association of digitalis and adverse outcome events in patients receiving implantable cardioverter defibrillators (ICDs) or cardiac resynchronization therapy defibrillators (CRT-Ds). Hence, we conducted this meta-analysis to assess the effect of digitalis on ICD or CRT-D recipients.

Methods

We systematically retrieved relevant studies using the Cochrane Library, PubMed, and Embase database. A random effect model was used to pool the effect estimates (hazard ratios (HRs) and 95% confidence intervals (CIs)) when the studies were of high heterogeneity, otherwise a fixed effect model was used.

Results

Twenty-one articles containing 44,761 ICD or CRT-D recipient

SUBMITTER: Zhuo W 

PROVIDER: S-EPMC9967079 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature