Different Dimensional Copper-Based Metal-Organic Frameworks with Enzyme-Mimetic Activity for Antibacterial Therapy.

ABSTRACT: Fighting against bacterial infection and accelerating wound healing remain important and challenging in infected wound care. Metal-organic frameworks (MOFs) have received much attention for their optimized and enhanced catalytic performance in different dimensions of these challenges. The size and morphology of nanomaterials are important in their physiochemical properties and thereby their biological functions. Enzyme-mimicking catalysts, based on MOFs of different dimensions, display varying degrees of peroxidase (POD)-like activity toward hydrogen peroxide (H₂O₂) decomposition into toxic hydroxyl radicals (•OH) for bacterial inhibition and accelerating wound healing. In this study, we investigated the two most studied representatives of copper-based MOFs (Cu-MOFs),

SUBMITTER: Lin C 

PROVIDER: S-EPMC9967080 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature