Molecular genotyping reveals mixed bovine and human trypanosomiasis in cattle from West Africa.

ABSTRACT:

Background and aim

Animal trypanosomiasis is a major contributor to agricultural and economic losses, especially in sub-Saharan Africa. We have shown that some animal species expressed genes that are significant players in immune response to bovine trypanosomosis, impeding signs and symptoms of the disease. We hypothesize that such animals are contributors to disease transmission dynamics and severe outcomes. Therefore, this study aims to ascertain trypanosome species diversity in cattle and their potential role as reservoirs for the transmission of human disease.

Materials and methods

We performed a molecular genotyping of trypanosome internal transcribed spacer 1 (ITS-1) and 18S ribosomal RNA genes on genomic DNA extracts from randomly sampled N'Dama cattle from slaughterh

SUBMITTER: Morenikeji OB 

PROVIDER: S-EPMC9967721 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature