Aspects of Phage-Based Vaccines for Protein and Epitope Immunization.

ABSTRACT: Because vaccine development is a difficult process, this study reviews aspects of phages as vaccine delivery vehicles through a literature search. The results demonstrated that because phages have adjuvant properties and are safe for humans and animals, they are an excellent vaccine tool for protein and epitope immunization. The phage genome can easily be manipulated to display antigens or create DNA vaccines. Additionally, they are easy to produce on a large scale, which lowers their manufacturing costs. They are stable under various conditions, which can facilitate their transport and storage. However, no medicine regulatory agency has yet authorized phage-based vaccines despite the considerable preclinical data confirming their benefits. The skeptical perspective of phages should be ove

SUBMITTER: Palma M 

PROVIDER: S-EPMC9967953 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature