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Early Exacerbation Relapse is Increased in Patients with Asthma and Bronchiectasis (a Post hoc Analysis).


ABSTRACT:

Purpose

Asthma is a common comorbidity in patients with bronchiectasis and has been shown to increase the risk of bronchiectasis exacerbations. This paper explores the impact of comorbid asthma on patients receiving intravenous antibiotic treatment for bronchiectasis exacerbations.

Methods

This was a post hoc analysis of the Meropenem randomised controlled trial of 90 patients that had intravenous antibiotic treatment for bronchiectasis exacerbations. The participants were split into two groups: group 1 (asthma and bronchiectasis) and group 2 (bronchiectasis). The authors assessed response to treatment and time to next exacerbation.

Results

There were 38 participants in group 1 and 34 participants in group 2. The groups were found to be comparable in terms of age, sex

SUBMITTER: Hill AR 

PROVIDER: S-EPMC9968257 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature