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Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management.

ABSTRACT: Stasis dermatitis is a chronic inflammatory skin disease of the lower extremities. It typically occurs in older individuals and is the cutaneous manifestation of venous hypertension caused by venous reflux. Such retrograde venous blood flow is the result of incompetent venous valves, valve destruction, or venous obstruction. Stasis dermatitis is eczematous. The associated impairment of venous valves may cause swelling of the legs, leading to serious conditions including venous ulcerations. Diagnosis can be challenging because of its clinical resemblance to other skin conditions and poor clinical recognition by physicians. The cornerstones of stasis dermatitis treatment are compression therapy to ameliorate pain and swelling, topical treatments to alleviate secondary skin changes, and interventional treatment options to correct the underlying causes of venous reflux. Given the central role of inflammation of the lower extremities in driving the cutaneous changes characteristic of stasis dermatitis, new therapeutic approaches that target the inflammation are under clinical evaluation in patients with stasis dermatitis.

SUBMITTER: Yosipovitch G

PROVIDER: S-EPMC9968263 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management.

Yosipovitch Gil G Nedorost Susan T ST Silverberg Jonathan I JI Friedman Adam J AJ Canosa Juliana M JM Cha Amy A

American journal of clinical dermatology 20230217 2

Stasis dermatitis is a chronic inflammatory skin disease of the lower extremities. It typically occurs in older individuals and is the cutaneous manifestation of venous hypertension caused by venous reflux. Such retrograde venous blood flow is the result of incompetent venous valves, valve destruction, or venous obstruction. Stasis dermatitis is eczematous. The associated impairment of venous valves may cause swelling of the legs, leading to serious conditions including venous ulcerations. Diagn ...[more]

PMID: 36800152

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Dataset Information

Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management.

Publications

Stasis Dermatitis: An Overview of Its Clinical Presentation, Pathogenesis, and Management.

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