The crucial role of adhesion in the transmigration of active droplets through interstitial orifices.

ABSTRACT: Active fluid droplets are a class of soft materials exhibiting autonomous motion sustained by an energy supply. Such systems have been shown to capture motility regimes typical of biological cells and are ideal candidates as building-block for the fabrication of soft biomimetic materials of interest in pharmacology, tissue engineering and lab on chip devices. While their behavior is well established in unconstrained environments, much less is known about their dynamics under strong confinement. Here, we numerically study the physics of a droplet of active polar fluid migrating within a microchannel hosting a constriction with adhesive properties, and report evidence of a striking variety of dynamic regimes and morphological features, whose properties crucially depend upon droplet speed and

SUBMITTER: Tiribocchi A 

PROVIDER: S-EPMC9968312 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature