Association between coronary artery disease and incident cancer risk: a systematic review and meta-analysis of cohort studies.

ABSTRACT:

Objective

Coronary artery disease (CAD) and cancer are the two leading causes of death worldwide. Evidence suggests the existence of shared mechanisms for these two diseases. We aimed to conduct a systematic review and meta-analysis to investigateassociation between CAD and incident cancer risk.

Methods

We searched Cochrane, PubMed, and Embase from inception until October 20, 2021, without language restrictions. Observational cohort studies were used to investigate the association between CAD and incident cancer risk. Using random-effects models, the odds ratio (OR) and 95% confidence interval (CI) were calculated. We utilized subgroup and sensitivity analyses to determine the potential sources of heterogeneity and explore the association between CAD and specific cancers. Th

SUBMITTER: Chen HH 

PROVIDER: S-EPMC9968460 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature