Current and future outlook of loaded components in hydrogel composites for the treatment of chronic diabetic ulcers

ABSTRACT: Due to recalcitrant microangiopathy and chronic infection, traditional treatments do not easily produce satisfactory results for chronic diabetic ulcers. In recent years, due to the advantages of high biocompatibility and modifiability, an increasing number of hydrogel materials have been applied to the treatment of chronic wounds in diabetic patients. Research on composite hydrogels has received increasing attention since loading different components can greatly increase the ability of composite hydrogels to treat chronic diabetic wounds. This review summarizes and details a variety of newly loaded components currently used in hydrogel composites for the treatment of chronic diabetic ulcers, such as polymer/polysaccharides/organic chemicals, stem cells/exosomes/progenitor cells, chelating

SUBMITTER: Cui J 

PROVIDER: S-EPMC9968980 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature