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Glycerol 3-phosphate inhibits swarming and aggregation of Myxococcus xanthus.


ABSTRACT: We have cloned a gene of Myxococcus xanthus with similarities to the permease for glycerol 3-phosphate (G3P) of other bacteria. Expression of the gene increased significantly during the first hours of starvation. Swarming of the wild-type strain was inhibited and aggregation was delayed by G3P. Conversely, a DeltaglpT strain aggregated even on rich medium. These results indicate that G3P may function to regulate the timing of aggregation in M. xanthus.

SUBMITTER: Moraleda-Munoz A 

PROVIDER: S-EPMC99693 | biostudies-literature | 2001 Oct

REPOSITORIES: biostudies-literature