Impact of Penicillin Allergy Labels on Children Treated for Outpatient Respiratory Infections.

ABSTRACT:

Background

Penicillin allergy is the most common antibiotic allergy, yet most children labeled as allergic tolerate penicillin. The impact of inaccurate penicillin allergy labels (PALs) on pediatric outpatients is unknown. The objective of this study was to compare outcomes between children with and without a PAL after treatment for outpatient respiratory tract infections (RTI).

Methods

A retrospective, longitudinal birth cohort study was performed in children who received care in 90 pediatric primary care practices in Philadelphia and Houston metropolitan areas. Prescribing and clinical outcomes of children with a PAL at the time of an RTI were compared to non-allergic children, adjusting for potential confounders.

Results

Antibiotics were prescribed for 663,473 non-

SUBMITTER: Joerger T 

PROVIDER: S-EPMC9969332 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature