Radiographic damage in early rheumatoid arthritis is associated with increased disability but not with pain-a 5-year follow-up study.

ABSTRACT:

Objectives

To evaluate how radiographic damage, overall and measured as joint space narrowing score (JSNS) and erosion score (ES), as well as other clinical and laboratory measures, relate to disability and pain in early rheumatoid arthritis (RA).

Methods

An inception cohort of 233 patients with early RA, recruited in 1995-2005, was followed for 5 years. Disability was assessed with the Health Assessment Questionnaire (HAQ), and pain with a visual analogue scale (VAS; 0-100 mm). Radiographs of hands and feet were evaluated using the Sharp-van der Heijde score (SHS), including JSNS and ES. The relation for radiographic scores and other clinical parameters with pain and HAQ were evaluated cross-sectionally by multivariate linear regression analysis and over time using generali

SUBMITTER: Eberhard A 

PROVIDER: S-EPMC9969673 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature