Descriptive and risk factor analysis of infantile cataracts: National Birth Defects Prevention Study, 2000-2011.

ABSTRACT: Using National Birth Defects Prevention Study (NBDPS) data, we sought to estimate birth prevalence, describe clinical characteristics, and examine risk factors for infantile cataracts. We calculated birth prevalence using the numbers of NBDPS-eligible cataract cases and live births in the study area. We described case infants by the presence of associated ipsilateral eye defects (IEDs) and non-eye-related major birth defects. Using maternal exposure information collected via telephone interview, we conducted logistic regression analyses among the interviewed cases and controls. Birth prevalence of infantile cataracts was 1.07/10,000 live births. Unilateral cataracts were more often associated with IEDs, while infants with bilateral cataracts were more often preterm, full-term with low birt

SUBMITTER: Nalbandyan M 

PROVIDER: S-EPMC9969683 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature