Exosomes as natural nanocarrier-based drug delivery system: recent insights and future perspectives.

ABSTRACT: Exosomes are nanosized (size ~ 30-150 nm) natural vesicular structures released from cells by physiological processes or pathological circumstances. Exosomes are growing in popularity as a result of their many benefits over conventional nanovehicles, including their ability to escape homing in the liver or metabolic destruction and their lack of undesired accumulation before reaching their intended targets. Various therapeutic molecules, including nucleic acids, have been incorporated into exosomes by different techniques, many of which have shown satisfactory performance in various diseases. Surface-modified exosomes are a potentially effective strategy, and it increases the circulation time and produces the specific drug target vehicle. In this comprehensive review, we describe compositi

SUBMITTER: Sen S 

PROVIDER: S-EPMC9970142 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature