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Systematic Literature Review of Economic Evaluations of Treatment Alternatives in Chronic Lymphocytic Leukemia.


ABSTRACT:

Background

Economic evaluations are widely used to predict the economic impact of new treatment alternatives. Comprehensive economic reviews in the field of chronic lymphocytic leukemia (CLL) are warranted to supplement the existing analyses focused on specific therapeutic areas.

Methods

A systematic literature review was conducted based on literature searches in Medline and EMBASE to summarize the published health economics models related to all types of CLL therapies. Narrative synthesis of relevant studies was performed focusing on compared treatments, patient populations, modelling approaches and key findings.

Results

We included 29 studies, the majority of which were published between 2016 and 2018, when data from large clinical trials in CLL became available. Tr

SUBMITTER: Lorenzovici L 

PROVIDER: S-EPMC9971131 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature